Adelaide Naturopath has observed that following a diet rich in fats and sugars present in ultra-processed foods (such as pastries) for a period of six weeks causes an increase in inflammatory molecules in the body, which increase the excitability of the muscular nerves, which is called musculoskeletal neurotransmission, making the person who followed these unhealthy eating habits more sensitive to muscle pain. The experiments were done on male Swiss mice. One group ate a typical cafeteria diet high in added sugars, such as pastries, and another ate a high-fat commercial diet, both for a period of six weeks. The intramuscular adipocytes, that is, the accumulation of fat, and the neuromuscular neurotransmission, which is the response of the muscular nerves that is evaluated by the electromyography procedure, were calculated. After the interruption of these diets rich in ultra-processed, the increase in neuromuscular neurotransmission lasted for several weeks. Intake of a cafeteria diet showed the presence of more adipocytes in muscle tissue , but the same did not happen with the high-fat diet. Both experimental groups, however, showed an increase in neuromuscular neurotransmission that lasted for several weeks after the diets were discontinued. The conclusion of the study was that feeding a hypercaloric diet for six weeks in mice increases neurotransmission, thus facilitating the development of muscle pain. After this period, the animals quickly regained their normal weight, but still followed the high neurotransmission parameters for several weeks. Being overweight is also linked to musculoskeletal painWestern societies have a clear increase in the rate of obesity and overweight . From 1975 to 2016 the global obesity rate tripled. By 2030, more than 38% of the world's adult population will be overweight and 20% will be obese. Obesity and overweight are considered an epidemic related to the development of various pathologies such as diabetes , cardiovascular diseases , metabolic syndrome and musculoskeletal pain.
Studies indicate that there is a strong relationship between obesity and pain. Typically, the association between being overweight and musculoskeletal pain has been attributed to increased mechanical stress caused by being overweight on load bearing joints (joints are spoiled by the weight they bear). However, the study that has just been published in the journal Nutrients "shows an association between pain and overweight independent of mechanical overload and is likely to involve systemic phenomena, those of the whole organism", explains Manel Santafè, one of the authors from work.
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May 2021
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